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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: J Cardiovasc Electrophysiol. 2015 Oct 13;27(1):110–119. doi: 10.1111/jce.12833

Figure 4. Metabolic stress uniformly reduced cellular excitability.

Figure 4

(A) Field stimulation of Ad368A monolayers during conduction block showed intact excitability (n=3). Similar action potentials were seen with field-stimulated of AdGFP monolayers (n=3). (B) INa elicited in NRVMs under baseline and MS conditions. INa significantly decreased with MS (p<0.01). (C) Summary data of INa at −20mV (AdGFP baseline n=7, MS n=8; AdCx43 n=7 each, Ad368A n=7 each, Ad368E baseline n=7, MS n=6). (D) Baseline sodium voltage dependent activation curve is shown for indicated virus (E) Summary of V(1/2 max) shows no difference among groups at baseline or MS (p=NS). AdGFP baseline n=7, MS n=8; AdCx43 n=7 each, Ad368A n=7 each, Ad368E baseline n=7, MS n=6.