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. Author manuscript; available in PMC: 2016 May 25.
Published in final edited form as: Contrast Media Mol Imaging. 2010 Nov 30;6(4):219–228. doi: 10.1002/cmmi.421

Figure 4.

Figure 4

Lorentzian line-fitting of a CEST spectrum. (A) A single function that consisted of a sum of three Lorentzian lines (solid line) was fit to the experimental data (solid circles) for a CEST spectrum of 7 mM of Yb-DO3A-oAA. Similar results were obtained from fitting other CEST spectra. (B) The residuals of the fitting routine (experimental data – fitted result, shown as solid circles connected with a line) were negligible near the peaks of the fitted Lorentzian lines for the CEST effects of the amine and amide (shown as solid lines that are peaked at +12 and −10 ppm, respectively).