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. 2016 Jun;22(6):1109–1112. doi: 10.3201/eid2206.152023

Table. Pre-PCV7 and post-PCV13 annualized pneumonia rates, by age, sex, and race, and hospitalizations per 1,000 children, Tennessee, USA, 1998–2013*.

Patient age, y, and race Patient sex Hospitalizations/1,000 children
Post-PCV13 vs. pre-PCV7
Pre-PCV7, 1998–1999, 11,059 hospitalizations Post-PCV13, 2011–2013, 9,171 hospitalizations Rate ratio 
(95% CI) Rate difference 
(95% CI)†
All‡

4.0
2.0

0.51 (0.50–0.52)
−2.0 (−2.1 to −1.9)
<2‡ 18.4 7.3 0.40 (0.38–0.41) −11.1 (−11.6 to −10.6)
Black M 27.1 8.5 0.31 (0.28–0.35) −18.6 (−20.5 to −16.6)
Black F 20.0 6.4 0.32 (0.28–0.37) −13.6 (−15.3 to −11.9)
White M 18.0 7.8 0.43 (0.40–0.46) −10.2 (−11.1 to −9.3)
White
F
14.5
6.2

0.43 (0.40–0.47)
−8.2 (−9.0 to −7.4)
2–4‡ 5.4 3.0 0.56 (0.52–0.59) −2.4 (−2.6 to −2.1)
Black M 6.6 3.4 0.50 (0.43–0.59) −3.3 (−4.1 to −2.5)
Black F 5.3 3.1 0.58 (0.49–0.70) −2.2 (−3.0 to −1.5)
White M 5.3 3.0 0.56 (0.51–0.62) −2.3 (−2.7 to −1.9)
White
F
5.0
2.9

0.59 (0.53–0.65)
−2.0 (−2.4 to −1.6)
5–17‡ 1.6 1.1 0.67 (0.63–0.70) −0.5 (−0.6 to −0.5)
Black M 2.0 1.1 0.57 (0.49–0.65) −0.8 (−1.1 to −0.6)
Black F 1.6 1.0 0.61 (0.53–0.71) −0.6 (−0.8 to −0.4)
White M 1.6 1.1 0.70 (0.65–0.75) −0.5 (−0.6 to −0.4)
White F 1.6 1.2 0.74 (0.68–0.80) −0.4 (−0.5 to −0.3)

*PCV7, 7-valent pneumococcal conjugate vaccine; PCV13, 13-valent pneumococcal conjugate vaccine.
†For hospitalizations per 1,000 children.
‡Includes all race/ethnicity categories (black, white, Hispanic, other). These estimates were not different from estimates including only black and 
white children.