Table 2.
Hemodynamics, Cardiac Structure, and Function: Response to Dietary Intervention
LCFA |
P Value LCFA Pre-Post | MCFA |
P Value MCFA Pre-Post | |||
---|---|---|---|---|---|---|
Pre | Post | Pre | Post | |||
Hemodynamics | ||||||
Heart rate (bpm) | 69 ± 3 | 65 ± 3 | NS | 75 ± 2a | 79 ± 2 | NS |
Systolic blood pressure (mmHg) | 138 ± 7 | 137 ± 7 | NS | 128 ± 6 | 127 ± 6 | NS |
Diastolic blood pressure (mmHg) | 80 ± 4 | 79 ± 4 | NS | 75 ± 4 | 75 ± 4 | NS |
LV structure | ||||||
Mass (g) | 221 ± 12 | 216 ± 12 | NS | 190 ± 11a | 179 ± 11 | NS |
Mass (g/BSA) | 50.1 ± 3.8 | 49.3 ± 3.8 | NS | 46.8 ± 3.3 | 43.9 ± 3.4 | NS |
Relative wall thickness | 0.6 ± 0.1 | 0.6 ± 0.1 | NS | 0.5 ± 0.1 | 0.5 ± 0.1 | NS |
LV diastolic function | ||||||
E′ average (cm/s) | 8.4 ± 0.7 | 8.5 ± 0.8 | NS | 8.4 ± 0.7 | 8.4 ± 0.7 | NS |
E/e′ (septal) | 11.6 ± 1.6 | 12.0 ± 1.6 | NS | 9.9 ± 1.4 | 9.1 ± 1.4 | NS |
Mitral valve deceleration time (ms) | 238 ± 15 | 225 ± 15 | NS | 204 ± 13 | 214 ± 13 | NS |
LV systolic function | ||||||
Ejection fraction (%) | 66 ± 2 | 64 ± 2 | NS | 65 ± 2 | 65 ± 2 | NS |
Abbreviation: NS, not significant.
Values are means ± SE. MCFA pre significantly different from LCFA pre:
P < .05. Measures of systolic function other than ejection fraction are shown as figures.