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Elevated plus maze performance in control animals (Con), animals exposed to TSE, or animals exposed to Nic at 0.2 or 2 mg/kg/d. Data represent means and SEs from 12 to 14 animals for each sex and treatment. A, Percentage of time spent in the open arms. B, Number of center crossings. ANOVA indicates significant main effects of treatment (P < .05) for both parameters.
