TABLE 1.
Control | CE | LPS | CE + LPS | |
---|---|---|---|---|
PLASMA (mg/dl) t = 24 h | ||||
Glu | 185 ± 20 | 249 ± 40 | 144 ± 30a | 139 ± 12a |
Chol | 51 ± 6 | 57 ± 4 | 67 ± 5 | 82 ± 6a,b |
HDL | 34 ± 9 | 36 ± 6 | 38 ± 4 | 51 ± 5a,b |
LDL | 8.8 ± 1.7 | 8.8 ± 1.4 | 6.8 ± 2.3 | 21 ± 5a,b |
VLDL | 11 ± 1 | 13 ± 2 | 27 ± 4a | 37 ± 7a,b |
TG | 54 ± 6 | 63 ± 10 | 134 ± 18a | 187 ± 37a,b |
LIVER (mg/g wet weight) t = 0 h | ||||
TG | 4.8 ± 0.5 | 9.5 ± 1.6a | ||
NEFA | 5.5 ± 0.1 | 6.2 ± 0.2a | ||
LIVER (mg/g wet weight) t = 24 h | ||||
TG | 5.3 ± 0.5 | 4.8 ± 0.1 | 27 ± 2a | 24 ± 3a |
NEFA | 5.1 ± 0.2 | 5.3 ± 0.3 | 6.1 ± 0.1a | 7.2 ± 0.2a,b |
Animals and treatments are described under “Methods” section. A lipid panel was measured with the Piccolo Xpress Chemistry analyzer in plasma samples. TG and nonesterified fatty acids were measured in hepatic lipid extracts. Data are mean 6 S.E.M. (n = 4–8) and are reported as indicated in the individual rows.
a, P < .05 compared with the absence of LPS;
b, P < .05 compared with the absence of CE.
Glu, glucose; Chol, cholesterol; HDL, high-density lipoprotein; LDL, low-density lipoprotein; VLDL, very low-density lipoprotein; TG, triglycerides; NEFA, nonesterified fatty acids.