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. 2016 Mar 8;151(2):312–323. doi: 10.1093/toxsci/kfw045

TABLE 1.

Effect of CE and LPS on Plasma Variables and Hepatic Lipids in Mice

Control CE LPS CE + LPS
PLASMA (mg/dl) t = 24 h
    Glu 185 ± 20 249 ± 40 144 ± 30a 139 ± 12a
    Chol 51 ± 6 57 ± 4 67 ± 5 82 ± 6a,b
    HDL 34 ± 9 36 ± 6 38 ± 4 51 ± 5a,b
    LDL 8.8 ± 1.7 8.8 ± 1.4 6.8 ± 2.3 21 ± 5a,b
    VLDL 11 ± 1 13 ± 2 27 ± 4a 37 ± 7a,b
    TG 54 ± 6 63 ± 10 134 ± 18a 187 ± 37a,b
LIVER (mg/g wet weight) t = 0 h
    TG 4.8 ± 0.5 9.5 ± 1.6a
    NEFA 5.5 ± 0.1 6.2 ± 0.2a
LIVER (mg/g wet weight) t = 24 h
    TG 5.3 ± 0.5 4.8 ± 0.1 27 ± 2a 24 ± 3a
    NEFA 5.1 ± 0.2 5.3 ± 0.3 6.1 ± 0.1a 7.2 ± 0.2a,b

Animals and treatments are described under “Methods” section. A lipid panel was measured with the Piccolo Xpress Chemistry analyzer in plasma samples. TG and nonesterified fatty acids were measured in hepatic lipid extracts. Data are mean 6 S.E.M. (n = 4–8) and are reported as indicated in the individual rows.

a, P < .05 compared with the absence of LPS;

b, P < .05 compared with the absence of CE.

Glu, glucose; Chol, cholesterol; HDL, high-density lipoprotein; LDL, low-density lipoprotein; VLDL, very low-density lipoprotein; TG, triglycerides; NEFA, nonesterified fatty acids.