Table 1.
Baseline Characteristics for Patients With PCOS and Controls
Baseline Characteristic | Study Arm |
P | |||
---|---|---|---|---|---|
PCOS | Non-PCOS | ||||
No. of patients | 9068 | 18 136 | |||
Followup (y), mean, sd | 4.2 | 3.3 | 4.2 | 3.3 | 1.000 |
Observation period pre-index (y), mean, sd | 5.3 | 3.7 | 6.5 | 3.8 | <.001 |
Age (y), mean, sd | 27.3 | 6.4 | 27.3 | 6.4 | .808 |
Ethnicity | |||||
Bangladeshi, n, % | 27 | 0.3 | 60 | 0.3 | <.001 |
Black (African/Caribbean/Other), n, % | 174 | 1.9 | 331 | 1.8 | |
Chinese, n, % | 13 | 0.1 | 22 | 0.1 | |
Indian, n, % | 173 | 1.9 | 173 | 1.0 | |
Mixed, n, % | 52 | 0.6 | 100 | 0.6 | |
Other Asian, n, % | 77 | 0.8 | 83 | 0.5 | |
Other, n, % | 103 | 1.1 | 202 | 1.1 | |
Pakistani, n, % | 143 | 1.6 | 160 | 0.9 | |
Unknown/not recorded, n, % | 2990 | 33.0 | 6701 | 36.9 | |
White, n, % | 5316 | 58.6 | 10 304 | 56.8 | |
Primary care contacts in previous year | 9.0 | 7.8 | 7.6 | 7.0 | <.001 |
Prescribed oral contraception ± 90 d of index date, n, % | 2712 | 29.9 | 6508 | 35.9 | <.001 |
History of assisted reproduction, n, % | 413 | 4.6 | 188 | 1.0 | <.001 |
BMI (kg/m2), mean, sd | 27.7 | 6.4 | 27.5 | 6.3 | .019 |
Underweight (< 18 kg/m2), n, % | 187 | 2.1 | 283 | 1.6 | <.001 |
Normal (18–25 kg/m2), n, % | 3543 | 39.1 | 7581 | 41.8 | |
Overweight (> 25–30 kg/m2), n, % | 2330 | 25.7 | 4543 | 25.0 | |
Obese (> 30–40 kg/m2), n, % | 2637 | 29.1 | 5013 | 27.6 | |
Extremely obese (> 40 kg/m2), n, % | 371 | 4.1 | 716 | 3.9 | |
BP | |||||
No. with BP recorded, n, % | 5378 | 59.3 | 15 529 | 85.6 | |
Systolic BP (mm Hg), mean, sd | 118.7 | 13.5 | 118.3 | 13.0 | .046 |
Diastolic BP (mm Hg), mean, sd | 74.8 | 9.7 | 73.5 | 9.6 | <.001 |
Hypertensive, n, % | 362 | 6.7 | 879 | 5.7 | .001 |
Smoking status | <.001 | ||||
Never smoked, n, % | 5159 | 56.9 | 9590 | 52.9 | |
Ex-smoker, n, % | 1511 | 16.7 | 3439 | 19.0 | |
Current smoker, n, % | 2364 | 26.1 | 5065 | 27.9 | |
Not recorded, n, % | 34 | 0.4 | 42 | 0.2 |
Abbreviation: BP, blood pressure.