Table 2.
Variable | TPTD (n = 21) |
PBO (n = 17) |
P-Value | ||
---|---|---|---|---|---|
Mean | sd | Mean | sd | ||
Structural | |||||
Cancellous bone volume, % | 17.51 | 3.01 | 17.03 | 4.64 | NS |
Trabecular thickness, μm | 117.4 | 15.54 | 119.4 | 15.92 | NS |
Trabecular number, No./mm | 1.49 | 0.18 | 1.41 | 0.30 | NS |
Trabecular separation, μm | 668.2 | 83.3 | 732.0 | 190.0 | NS |
Cortical width, μm | 866.2 | 258.3 | 917.9 | 227.0 | NS |
Cortical porosity area, % | 10.56 | 3.64 | 9.49 | 2.79 | NS |
Cortical porosity number, No./mm2 | 5.17 | 1.32 | 4.80 | 1.48 | NS |
Cancellous | |||||
Osteoclast number/BS | 0.072 | 0.062 | 0.052 | 0.049 | NS |
Osteoid volume/BV, % | 0.523 | 0.484 | 0.625 | 1.116 | NS |
Osteoid surface/BS, % | 4.17 | 3.75 | 2.83 | 3.55 | NS |
Osteoid thickness, μm | 4.98 | 0.72 | 5.73 | 1.39 | .056 |
Wall thickness, μm | 25.13 | 2.54 | 26.13 | 1.77 | NS |
Eroded surface/BS, % | 3.36 | 1.57 | 3.12 | 1.21 | NS |
Adjusted apposition rate, μm/d | 1.59 | 1.03 | 1.17 | 0.70 | .16 |
Activation frequency, cycle/y | 0.712 | 0.571 | 0.305 | 0.263 | .007 |
Endocortical | |||||
Osteoclast number/BS | 0.102 | 0.102 | 0.091 | 0.083 | NS |
Osteoid surface/BS, % | 8.95 | 7.71 | 5.73 | 4.72 | .12 |
Osteoid thickness, μm | 5.08 | 1.11 | 5.82 | 0.76 | .02 |
Wall thickness, μm | 27.70 | 2.86 | 29.43 | 1.85 | .037 |
Eroded surface/BS, % | 4.49 | 2.19 | 4.89 | 3.01 | NS |
Adjusted apposition rate, μm/d | 1.67 | 1.02 | 1.39 | 1.07 | NS |
Activation frequency, cycle/y | 1.41 | 0.90 | 0.73 | 0.48 | .006 |
Intracortical | |||||
Osteoclast number/BS | 0.224 | 0.201 | 0.156 | 0.128 | NS |
Osteoid surface/BS, % | 5.16 | 3.83 | 6.06 | 3.90 | NS |
Osteoid thickness, μm | 5.12 | 1.04 | 6.09 | 0.81 | .003 |
Wall thickness, μm | 34.88 | 3.79 | 36.25 | 2.33 | NS |
Eroded surface/BS, % | 6.43 | 4.16 | 4.81 | 2.44 | .15 |
Adjusted apposition rate, μm/d | 3.01 | 2.52 | 1.62 | 0.67 | .02 |
Activation Frequency, cycle/y | 1.08 | 0.60 | 0.98 | 0.66 | NS |
Abbreviation: NS, not significant.