Table 4. Gene candidates in KEGG reference cytokine-cytokine receptor interaction pathway after within-experiment enrichment analysis.
| Classification | CONSOL | REC | EXTNOR | OPLS-DA-set | Expression Set | k-means* |
|---|---|---|---|---|---|---|
| Chemokines | Cxcl1 | R964 | R200mso | Profile CD | ||
| Cxcl3 | R964 | R200mso | ||||
| Cxcl9 | R964 | Profile CD | ||||
| Cxcl10 | R964 | |||||
| Cxcl11 | R964 | Profile CD | ||||
| Cxcl13 | R964 | R200mso | ||||
| Cxcr2 | R964 | R200mso | Profile CD | |||
| Cxcl12 | E969 | E200ext | ||||
| CC-subfamily | Ccl2 | R964 | ||||
| Ccl3 | R964 | R200mso | Profile CD | |||
| Ccl4 | R964 | R200mso | ||||
| Ccl6 | R964 | R200mso | ||||
| Ccl9 | R964 | |||||
| Ccl20 | R964 | Profile CD | ||||
| Ccl27 | R964 | R200aso | ||||
| Ccbp2 | E969 | E200nor | ||||
| Hematopoietins | Epor | C1150 | ||||
| Il11ra1 | C1150 | C200mso | ||||
| Prlr | C1150 | |||||
| Csf2ra | R964 | |||||
| Csf3r | R964 | |||||
| Il6 | R964 | R200mso | ||||
| Il13ra1 | R964 | Profile CD | ||||
| Il6st | E969 | E200ext | ||||
| Il23a | E969 | E200nor | ||||
| PDGF-family | Pdgfra | C1150 | C200mso | Profile A | ||
| Csf1 | R964 | R200mso | Profile CD | |||
| Kitlg | R964 | |||||
| Vegfc | R964 | |||||
| Csf1r | E969 | E200ext | ||||
| Egfr | E969 | |||||
| Flt1 | E969 | E200ext | ||||
| Kdr | E969 | |||||
| Pdgfd | E969 | |||||
| Pdgfrb | E969 | |||||
| Interferons | Ifnar1 | E969 | E200ext | Profile A | ||
| Il10-family | Il10rb | Il10rb | R964, E969 | E200ext | ||
| TNF-family | Tnfsf13 | C1150 | C200mso | Profile B | ||
| Tnfrsf1a | R964 | |||||
| Tnfrsf1b | R964 | R200mso | ||||
| Tnfrsf12a | R964 | R200mso | Profile CD | |||
| Tnfrsf14 | R964 | Profile CD | ||||
| Tnfrsf26 | R964 | R200mso | ||||
| Tnfrsf4 | E969 | |||||
| Tnfrsf11b | E969 | E200ext | ||||
| Tnfrsf14 | E969 | E200nor | Profile CD | |||
| Tnfsf12 | E969 | Profile A | ||||
| TGFβ -family | Bmp4 | C1150 | C200mso | Profile B | ||
| Tgfaa | C1150 | C200mso | ||||
| Bmpr2 | E969 | E200ext | ||||
| Tgfb2 | E969 | |||||
| Tgfb3 | E969 | |||||
| Tgfbr2 | E969 | Profile A | ||||
| Il1-family | Il1a | R964 | R200mso | Profile CD | ||
| Il1b | R964 | |||||
| Il1rn | R964 |
Genes more highly expressed in the groups that are associated with consolidation, recall and extinction (CMSO, RMSO and EXT, respectively) are in bold. Genes down regulated in those states that are not in bold.
* k-means clustering for the pattern or profile of fold changes across all data sets (see Fig 4).