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. 2016 May 25;11(5):e0155832. doi: 10.1371/journal.pone.0155832

Table 3. Summary of additional VWF SNPs analysis and association in 115 HSE cases and 158 EIMS controls.

Scandinavian All individuals
SNP marker Position Minor Allele MAF cases MAF controls OR (95% CI) P-value OR (95% CI) P-value
rs12369177 5943781 T 0.404 0.366 0.97 (0.65–1.43) 0.86 1.18 (0.81–1.70) 0.39
rs11063961 5944277 G 0.191 0.187 1.00 (0.69–1.45) 0.98 1.02 (0.71–1.47) 0.90
rs12300917 5949319 A 0.149 0.190 0.80 (0.54–1.21) 0.29 0.75 (0.51–1.11) 0.15
rs7301070 5950551 G 0.423 0.314 1.46 (0.98–2.16) 0.06 1.61 (1.11–2.33) 0.01
rs2238110 5950838 G 0.423 0.314 1.46 (0.98–2.16) 0.06 1.61 (1.11–2.33) 0.01
rs917857 5952085 A 0.415 0.478 0.75 (0.55–1.00) 0.05 0.77 (0.58–1.03) 0.08
rs917858 5952199 C 0.423 0.316 1.43 (0.97–2.13) 0.07 1.59 (1.09–2.30) 0.01
rs917859 5952374 A 0.423 0.329 1.50 (1.11–2.02) 0.008 1.50 (1.12–2.00) 0.006
rs2239138 5952819 A 0.427 0.314 1.46 (0.98–2.16) 0.06 1.63 (1.13–2.37) 0.009
rs12829271 5953060 A 0.427 0.314 1.46 (0.98–2.16) 0.06 1.63 (1.13–2.37) 0.009
rs4764521 5954584 A 0.254 0.213 1.27 (0.91–1.79) 0.16 1.26 (0.91–1.76) 0.16

MAF = minor allele frequency; HWE = Hardy-Weinberg Equilibrium; OR = odds ratio; CI = confidence interval. (Chr12 SNPs positions (in bp) (Genome build 36.3). Table summarizing the analysis of the new 6 and 3 associated SNPs (the analysis was run in a total of 36 SNPs, data not shown).

Scandinavian columns: represent analysis of OR and P-value made in Scandinavian 115 HSE cases and 428 EIMS controls;

All individuals columns: represent analysis of OR and P-value made in Scandinavian and non-Scandinavian 119 HSE cases and 508 EIMS controls.