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. 2016 May 25;10(5):e0004614. doi: 10.1371/journal.pntd.0004614

Fig 4. Anti-leishmanial activity of canine monocyte-derived macrophages in non-immune and immune dogs.

Fig 4

The ability of pre-infected canine monocyte-derived macrophages to kill Leishmania parasites when they were exposed to autologous peripheral lymphocytes derived from PBMC was expressed as the percentage of parasitic index inhibition after in vitro infection with Leishmania infantum promastigotes (MHOM/MA/67/ITMAP-263) and 72 h incubation with and without autologous lymphocytes. Anti-leishmanial activity of co-cultured canine macrophages was evaluated immediately before immunization and two months after the third dose. Values represent means +/- standard deviation of duplicate experiments (* p< 0.05, ** p<0.01, *** p<0.001).