Fig 1. The graph illustrates the correlation between the histological classification (AHA^4-5) and the expression of macrophage membrane pattern.

The line chart witnessed an evident increasing of macrophage membrane pattern in VI class plaques. The histological classification of AHA defines VI class lesions as atheroma. Usually, type VI lesions episodes may quickly lead to occlusion and to be symptomatic for patients. It highlights our theories that the immunochemical ST2 membrane pattern has a direct correlation in terms of symptoms, and it could be a marker to detect vulnerable plaques.