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. Author manuscript; available in PMC: 2016 Oct 18.
Published in final edited form as: Nat Chem. 2016 Apr 18;8(6):556–562. doi: 10.1038/nchem.2493

Figure 2. Distribution of Mutations Selected in Evolved Polymerases.

Figure 2

Mutation sites have been coloured by their representation among evolved polymerases. Mutation sites shared by SFM4-3, SFM4-6, and SFM4-9 (red); sites shared by SFM4-3 and SFM4-9 (yellow); and sites unique to SFM4-3 (blue) or SFM4-9 (purple). Also highlighted are the primer strand (orange) and the template strand (pale blue). Residue labels correspond to the wild type Sf protein. (PDB ID: 3KTQ)