Table 1.
Summary of trends in levels of cecal metabolites in C57BL/6 transplanted mice (Group II vs Group I).
| Super Pathway | Sub-pathway | Metabolite | Fold change (Group II vs I) | p value |
|---|---|---|---|---|
| Amino acid | Phenylalanine metabolism | Benzoic Acid | 1.01 | 0.031786 |
| Amino acid | Alanine, aspartate and Glutamate metabolism | N-acetylasparagine | 0.52 | 0.066953 |
| Amino acid | Tryptophan metabolism | Xanthurenic acid | 7.55 | 0.072748 |
| Amino acid | Urea cycle | Homocitrulline | 2.7 | 0.075261 |
| Amino acid | Arginine and proline metabolism | N-acetyl-glutamate | 1.68 | 0.08886 |
| Amino acid | Phenylalanine metabolism | phenylpyruvate | 3.3 | 0.094054 |
| Carbohydrate | Pentose phosphate pathway | Sedoheptulose-7- phosphate | 0.99 | 0.05242 |
| Cofactors and vitamins | Microbial metabolism in diverse environments | cresol | 0.13 | 0.019692 |
| Lipid | Fatty acids | Hexanedioic acid | 42.32 | 0.0053711 |
| Lipid | Long chain fatty acid | Linoleic acid | 1.95 | 0.011101 |
| Lipid | Long chain fatty amide | Oleamide | 0.46 | 0.030305 |
| Lipid | Long chain fatty acid | dihydroxystearic acid | 1.02 | 0.042845 |
| Lipid | Long chain fatty amide | Stearamide | 0.09 | 0.068105 |
| Nucleotide | Purine metabolism | cAMP | 0.99 | 0.077892 |
Data were analyzed using comprehensive global mass spectrometry-based metabolomics analysis. Additional details are provided in Experimental Procedures.