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Binding Affinities of Compounds 1–8, Δ9-THC, and Δ8-THC
| compound | binding affinity (nM)
|
|
|---|---|---|
| CB1 | CB2 | |
| 1 | 1906 ± 578 | 3219 ± 876 |
| 2 | 65 ± 16 | 88 ± 19 |
| 3 | 31 ± 6 | 30 ± 4 |
| 4 | 830 ± 94 | 3274 ± 515 |
| 5 | 117 ± 16 | 129 ± 13 |
| 6 | 224 ± 20 | 335 ± 36 |
| 7 | 47 ± 18 | 912 ± 77 |
| 8 | 5668 ± 1324 | 2143 ± 353 |
| Δ8-THC | 78 ± 5 | 12 ± 2 |
| Δ9-THC | 18 ± 4 | 42 ± 9 |
