Table 2.
Characteristics of normal controls and patients with Barrett’s esophagus or esophageal adenocarcinoma used for validation by Q-RT-PCR
| Variable | Controls (n = 15) | BE (n = 41) | EAC (n = 59) |
|---|---|---|---|
| Gender (male) | 3 (20 %) | 31 (76 %) | 53 (90 %) |
| Age (years, mean ± SD and range) | 39.5 ± 14.7 (19–68) | 59.2 ± 11.7 (35–81) | 65.8 ± 10.8 (42–85) |
| Barrett length (mean and range) | na | C3M4 (C0M2–C10M11) | C5M8 (C0M2–C14M14) |
| Tumor stage (T) | |||
| 1 | na | na | 6 (10 %) |
| 2 | 10 (17 %) | ||
| 3 | 36 (61 %) | ||
| 4 | 1 (2 %) | ||
| X (unknown) | 6 (10 %) | ||
| Lymph node status (N) | |||
| 0 | na | na | 22 (37 %) |
| 1 | 24 (41 %) | ||
| 2 | 6 (10 %) | ||
| 3 | 1 (2 %) | ||
| 4 | 0 (0 %) | ||
| X | 6 (10 %) | ||
| Metastasis (M) | |||
| 0 | na | na | 6 (10 %) |
| 1 | 8 (14 %) | ||
| X | 45 (76 %) | ||
| Body mass index (mean ± SD) | 24.5 ± 4.0 | 25.6 ± 2.6 | 25.3 ± 2.9 |
| Current smokers | 3 | 6 | 4 |
| Previous smokers | 3 | 4 | 7 |
| Non-smokers | 9 | 6 | 6 |
| Unknown | 25 | 42 | |
BE Barrett’s esophagus, EAC esophageal adenocarcinoma, CM circumference length, maximum length