Table 3.

MicroRNA expression in plasma samples; profiling study

MicroRNA ID	Mean expression controls	Mean expression BE	Mean expression EAC	Fold induction BE/controls	Fold induction EAC/controls	Fold induction EAC/BE
hsa-let-7d-3p	1.02	0.78	0.85	0.76 (p = 0.011)	0.83	1.09
hsa-let-7e-5p	1.22	1.08	1.61	0.88	1.32	1.50 (p = 0.038)
hsa-miRNA-1-3p	1.74	0.61	0.51	0.35	0.29	0.84
hsa-miRNA-10a-5p	1.01	0.64	0.57	0.63	0.56 (p = 0.018)	0.89
hsa-miRNA-92b-3p	1.13	0.88	0.72	0.77	0.64	0.82
hsa-miRNA-95-3p	1.18	2.61	0.93	2.21	0.79	0.36
hsa-miRNA-122-5p	1.09	1.65	1.07	1.52	0.99	0.65
hsa-miRNA-127-3p	1.31	0.79	1.30	0.60	0.99	1.65
hsa-miRNA-133a-3p	1.64	0.51	0.52	0.31	0.32	1.02
hsa-miRNA-133b	2.21	0.71	0.70	0.32	0.32	0.99
hsa-miRNA-136-5p	1.17	0.68	1.43	0.58	1.22	2.11
hsa-miRNA-154-5p	1.31	0.84	1.32	0.64	1.01	1.58
hsa-miRNA-186-5p	1.01	0.86	1.05	0.86	1.04	1.21 (p = 0.01)
hsa-miRNA-194-5p	1.12	2.47	2.55	2.21	2.28	1.03
hsa-miRNA-195-5p	1.00	1.25	1.46	1.24	1.45 (p = 0.02)	1.17
hsa-miRNA-365a-3p	1.07	0.87	0.67	0.82	0.62 (p = 0.02)	0.76
hsa-miRNA-382-5p	1.15	0.76	1.57	0.65	1.36	2.08 (p = 0.007)
hsa-miRNA-451a	1.10	2.01	1.29	1.83 (p = 0.029)	1.18	0.64
hsa-miRNA-500a-5p	1.09	0.77	0.65	0.71	0.59	0.84
hsa-miRNA-532-3p	1.03	0.96	0.74	0.93	0.71	0.77 (p = 0.038)
hsa-miRNA-574-3p	1.02	0.87	0.72	0.85	0.71 (p = 0.043)	0.83
hsa-miRNA-1974	1.39	3.20	1.73	2.31	1.25	0.54

MicroRNAs significantly (p < 0.05) or more than 1.5-fold up- or down-regulated comparing plasma samples from esophageal adenocarcinoma (EAC), Barrett’s esophagus (BE), and controls. Mean expression along with their fold induction are shown