Table 2.
Effect of A. biebersteinii essential oil (ABEO) on induced hepatotoxicity-related parameters.
| Treatment group (n = 6) | SGOT (U/L) | SGPT (U/L) | GGT (U/L) | ALP (U/L) | Bilirubin (mg/dL) |
|---|---|---|---|---|---|
| Normal control | 79.66 ± 4.40 | 42.83 ± 2.77 | 7.58 ± 0.27 | 346.33 ± 9.40 | 0.57 ± 0.01 |
| CCl4 only | 319.33 ± 10.85∗∗∗a | 270.16 ± 21.23∗∗∗a | 19.15 ± 1.19∗∗∗a | 624.83 ± 11.76∗∗∗a | 2.84 ± 0.17∗∗∗a |
| ABEO (0.2 mL/kg + CCl4) | 217.22 ± 9.75∗∗∗ | 176.83 ± 8.13∗∗ | 11.08 ± 0.57∗∗∗ | 535.33 ± 12.36∗∗ | 1.80 ± 0.07∗∗∗ |
| Silymarin (10 mg/kg + CCl4) | 147.5 ± 10.85∗∗∗b | 118.18 ± 7.48∗∗∗b | 9.06 ± 0.35∗∗∗b | 413.81 ± 13.60∗∗b | 1.29 ± 0.08∗∗∗b |
All values represent mean ± SEM. ∗ p < 0.05; ∗∗ p < 0.01; ∗∗∗ p < 0.001; ANOVA, followed by Dunnett's multiple comparison test. aAs compared with normal group. bAs compared with CCl4 only group.