Table 3. Distribution of DPD mutations.

DPD mutation	Number (n=22) [%]
IVS14+1G→A (exon 14)	12 [39]
Heterozygous	8 [26]
Homozygous	4 [13]
85 T→C (exon 2)	8 [36]
Heterozygous	4 [18]
Homozygous	4 [18]
1627 A→G (exon 13)	7 [31]
Heterozygous	6 [27]
Homozygous	1 [4]
496 A→G (exon 6)	4 [18]
Heterozygous	2 [9]
Homozygous	2 [9]
2194 G→A (exon 18)	4 [18]
Heterozygous	4 [18]
Homozygous	0 [0]
Single mutation	11 [50]
More than one mutation	11 [50]

DPD, dihydropyrimidine dehydrogenase.