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. 2016 May 26;16:231. doi: 10.1186/s12879-016-1536-9

Table 1.

Setting-specific model inputs for Analyses II and III, adapted from the global model [4] and adopting all other global model assumptions, including generic inputs from the DEB model.[16, 17]

Region R0 α pd κ tr POL3 TC Prm poro # tOPV SIAs in 2015 Year of IPV introduction Hypothetical switch date
Analysis II:
Hypothetical population 10 or 13 0 NA 0.35 0.6 0.3 0.8 0.7 0.3 2 2015 Variable after last SIA in 2015
Analysis III:
Population like northern India 13 0.2 180 0.35 0.6 0.3 2 2015
 - Pop. A, subpop. 0 (under-vacc.) 0.3 0.8 0.7 Mid-2015
 - Pop. A, subpop. 1 (general) 0.6 0.95 0.5 Mid-2015
 - Pop. B, subpop. 0 (under-vacc.) 0.3 0.8 0.7 April 1, 2016
 - Pop. B, subpop 1 (general) 0.6 0.95 0.5 April 1, 2016
Population like northern Pakistan/Afghanistan 11 0.2 180 0.35 0.65 0.3 2015
 - Pop. A, subpop. 0 (general) 0.6 0.8 0.7 2 Mid-2015
 - Pop. A, subpop. 1 (general) 0.6 0.8 0.7 2 Mid-2015
 - Pop. B, subpop. 0 (under-vacc.) 0.1 0.35 0.95 3 April 1, 2016
 - Pop. B, subpop 1 (general) 0.6 0.8 0.7 2 April 1, 2016
Population like Ukraine 6 0.4 180 0.45 0.74 0.8 0 2005
 - Pop. A, subpop. 0 (general) 0.7a 0.8 0.7 Mid-2015 
 - Pop. A, subpop. 1 (general) 0.7a 0.8 0.7 Mid-2015
 - Pop. B, subpop. 0 (under-vacc.) 0.3 a 0.8 0.7 April 1, 2016
 - Pop. B, subpop 1 (under-vacc. ) 0.3a 0.8 0.7 April 1, 2016

Model input symbols: [3, 16] R 0 average annual basic reproduction number for WPV of serotype 1, α seasonal amplitude of R0, defined as the “proportional change in R0 due to seasonality” [16, p. 717], pd peak day of R0, κ strength of preferential mixing between age groups, defined as the “proportion of contacts reserved for individuals within the same mixing age group”[16, p. 717], tr take rate of serotype 2 tOPV, POL3 RI coverage with 3 or more non-birth doses, TC true coverage of each SIA, P rm repeated missed probability of each SIA, poro, proportion of transmissions via oropharyngeal route

aAssume POL3 = 90 % prior to 2010