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Aprepitant plasma and CSF concentrations in non-human primates. a Plasma aprepitant concentrations measured in rhesus monkeys (n = 3/group) following daily oral doses of 80 mg (square) or 125 mg (triangle). Data reflects mean aprepitant plasma concentrations on dense sampling days (1, 7 and 14) + SD. b Plasma (Cp) and CSF steady-state trough concentrations presented as box-n-whisker plots
