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. 2016 May 26;6:26807. doi: 10.1038/srep26807

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Copyright © 2016, Macmillan Publishers Limited

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Concentration-dependent vasorelaxation of aortic segments in response to acetylcholine (Ach) (a) and S-nitroso-N-acetylpenicillamine (SNAP) (b) n = 8 segments/group from 10–12 rats. Values are mean ± SEM. ND: normal diet group, HFD: high-fat diet group, HFD + V: high-fat diet + saline group, HFD + U: high-fat diet + U50,488H group, HFD + N: high-fat diet + nor-BNI group, HFD + U + N: high-fat diet + U50,488H + nor-BNI group. *P < 0.05, **P < 0.01 vs. ND, ^##P < 0.01 vs. HFD, ^&&P < 0.01, vs. HFD + V, ^$$P < 0.01, vs. HFD + U.