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. 2016 May 26;14:39. doi: 10.1186/s12951-016-0193-x

Table 1.

The engagement of aptamer-based nanoformulations in anti-cancer therapy

Type Nanoformulation Indication Reference
Anti-HER2 aptamer (HApt) Gold nanoparticles HER-2 positive breast cancer [207]
CD133 aptamer Salinomycin-loaded PEGylated PLGA nanoparticles Osteosarcoma [208]
CD133 aptamers A15 and EGFR aptamers CL4 Salinomycin-loaded PLGA nanoparticles Hepatocellular carcinoma [209]
EGFR-targeting aptamers Triple-functional pRNA-3WJ nanoparticles Triple-negative breast cancer [210]
EpCAM aptamer Doxorubicin-loaded PEG-PLGA nanoparticles Non-small cell lung cancer [211]
Mucin 1 aptamer Gold nanoparticle-hybridized graphene oxide Breast cancer [212]