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. 2016 Mar 8;28(1):32–36. doi: 10.1016/j.joco.2016.01.003

Table 2.

Single nucleotide polymorphism analyzed in 44 nonvascular AMD patients.

Gene SNP Base changea Total frequency (%) Frequency of homozygous common allele Frequency of heterozygous allele Frequency of homozygous rare allele
CFH rs203674 C→A 90.90% 0.365 0.414 0.219
CFH rs572515 T→C 93.18% 0.341 0.414 0.243
CFH rs800292 C→A 77.27% 0.735 0.26 0
CFH rs1061147 A→C 100% 0.509 0.372 0.117
CFH rs1061170 C→T 70.45% 0.387 0.483 0.129
CFH rs2274700 C→T 95.45% 0.547 0.285 0.166
CFH rs7529589 T→C 88.63% 0.358 0.512 0.128
CFH rs12038333 G→A 90.90% 0.35 0.45 0.2
CFH rs35507625 del 93.18% 0.829 0.121 0.04
LOC387715/ARMS2 rs11200638 A→G 63.63% 0.5 0.357 0.142
LOC387715/ARMS2 rs10664316 Del AT 86.36% 0.552 0.342 0.105
HTRA1 rs2672598 G→A 52.27% 0.565 0.434 0

CFH = complement factor H gene, ARMS2 = age-related maculopathy susceptibility 2 gene, HTRA1 = HtrA serine peptidase 1 gene, SNP = single nucleotide polymorphism.

a

Base change is written common allele > rare allele.