Table 2.
Gene | SNP | Base changea | Total frequency (%) | Frequency of homozygous common allele | Frequency of heterozygous allele | Frequency of homozygous rare allele |
---|---|---|---|---|---|---|
CFH | rs203674 | C→A | 90.90% | 0.365 | 0.414 | 0.219 |
CFH | rs572515 | T→C | 93.18% | 0.341 | 0.414 | 0.243 |
CFH | rs800292 | C→A | 77.27% | 0.735 | 0.26 | 0 |
CFH | rs1061147 | A→C | 100% | 0.509 | 0.372 | 0.117 |
CFH | rs1061170 | C→T | 70.45% | 0.387 | 0.483 | 0.129 |
CFH | rs2274700 | C→T | 95.45% | 0.547 | 0.285 | 0.166 |
CFH | rs7529589 | T→C | 88.63% | 0.358 | 0.512 | 0.128 |
CFH | rs12038333 | G→A | 90.90% | 0.35 | 0.45 | 0.2 |
CFH | rs35507625 | del | 93.18% | 0.829 | 0.121 | 0.04 |
LOC387715/ARMS2 | rs11200638 | A→G | 63.63% | 0.5 | 0.357 | 0.142 |
LOC387715/ARMS2 | rs10664316 | Del AT | 86.36% | 0.552 | 0.342 | 0.105 |
HTRA1 | rs2672598 | G→A | 52.27% | 0.565 | 0.434 | 0 |
CFH = complement factor H gene, ARMS2 = age-related maculopathy susceptibility 2 gene, HTRA1 = HtrA serine peptidase 1 gene, SNP = single nucleotide polymorphism.
Base change is written common allele > rare allele.