Table 2.
Controls | Subclinical keratoconus | Definite keratoconus |
Subclinical vs. controls |
Definite vs. controls |
|||
---|---|---|---|---|---|---|---|
Mild | Moderate | Severe | p value | p value | |||
Mean K | 43.8 ± 1.4 | 43.1 ± 1.2 | 46.1 ± 2.0 | 50.6 ± 2.3 | 53.4 ± 5.9 | 0.443 | <0.001 |
AEmax | 8.70 ± 4.6 | 12.39 ± 8.0 | 26.95 ± 12.8 | 41.93 ± 15.5 | 54.42 ± 22.2 | 0.346 | <0.001 |
PEmax | 14.60 ± 6.0 | 24.02 ± 12.8 | 48.72 ± 19.5 | 72.87 ± 23.7 | 93.94 ± 29.1 | 0.012 | <0.001 |
Topometric indices | |||||||
ISV | 19 ± 7 | 28 ± 13 | 62 ± 24 | 96 ± 23 | 133 ± 34 | 0.002 | <0.001 |
IVA | 0.10 ± 0.0 | 0.28 ± 0.2 | 0.69 ± 0.3 | 0.97 ± 0.4 | 1.25 ± 0.5 | <0.001 | <0.001 |
KI | 1.02 ± 0.02 | 1.05 ± 0.05 | 1.15 ± 0.10 | 1.25 ± 0.10 | 1.36 ± 0.17 | <0.001 | <0.001 |
CKI | 1.00 ± 0.00 | 1.00 ± 0.01 | 1.03 ± 0.03 | 1.07 ± 0.04 | 1.12 ± 0.06 | <0.001 | <0.001 |
IHA | 3.39 ± 2.80 | 7.04 ± 6.08 | 20.90 ± 15.08 | 25.24 ± 15.96 | 35.10 ± 24.54 | 0.131 | <0.001 |
IHD | 0.006 ± 0.003 | 0.017 ± 0.012 | 0.051 ± 0.027 | 0.080 ± 0.034 | 0.122 ± 0.049 | <0.001 | <0.001 |
Rmin | 7.49 ± 0.25 | 7.47 ± 0.20 | 6.59 ± 0.32 | 5.83 ± 0.12 | 5.13 ± 0.44 | 0.331 | <0.001 |
Pachymetric indices | |||||||
TP | 537 ± 31 | 499 ± 32 | 473 ± 38 | 439 ± 40 | 415 ± 58 | <0.001 | <0.001 |
RPIavg | 0.99 ± 0.14 | 1.23 ± 0.34 | 1.80 ± 0.52 | 2.50 ± 0.55 | 3.39 ± 1.24 | <0.001 | <0.001 |
RPImax | 1.23 ± 0.20 | 1.71 ± 0.48 | 2.55 ± 0.86 | 3.35 ± 0.80 | 4.67 ± 2.00 | <0.001 | <0.001 |
ARTavg | 555 ± 94 | 435 ± 124 | 282 ± 93 | 185 ± 51 | 140 ± 69 | <0.001 | <0.001 |
ARTmax | 449 ± 82 | 319 ± 107 | 202 ± 67 | 139 ± 37 | 103 ± 46 | <0.001 | <0.001 |
BAD_D | 0.96 ± 0.8 | 3.34 ± 2.9 | 6.94 ± 2.9 | 10.77 ± 3.2 | 15.52 ± 6.4 | <0.001 | <0.001 |
Aberrometric indices | |||||||
RMS total | 1.70 ± 0.84 | 2.46 ± 1.40 | 6.64 ± 2.95 | 10.10 ± 3.61 | 15.65 ± 5.85 | <0.001 | <0.001 |
RMS HOA | 0.34 ± 0.08 | 0.66 ± 0.39 | 1.70 ± 0.84 | 2.59 ± 0.97 | 4.01 ± 1.74 | <0.001 | <0.001 |
3rd Ver. coma total | −0.05 ± 0.17 | −0.42 ± 0.41 | −1.32 ± 0.90 | −1.98 ± 1.20 | −2.76 ± 2.03 | <0.001 | <0.001 |
3rd Ver. coma front | −0.13 ± 0.51 | −1.53 ± 1.41 | −4.68 ± 3.02 | −7.00 ± 4.05 | −9.84 ± 6.5 | <0.001 | <0.001 |
3rd Ver. coma back | 0.186 ± 1.07 | −3.50 ± 3.28 | −10.02 ± 6.21 | −14.49 ± 7.93 | −19.91 ± 10.75 | <0.001 | <0.001 |
3rd Hor. coma total | 0.000 ± 0.123 | 0.012 ± 0.262 | −0.034 ± 0.631 | 0.022 ± 1.011 | 0.041 ± 1.660 | 0.605 | 0.929 |
3rd Hor. coma front | −0.016 ± 0.385 | 0.000 ± 0.889 | −0.124 ± 2.18 | 0.069 ± 3.65 | 0.293 ± 5.64 | 0.837 | 0.934 |
3rd Hor. coma back | −0.144 ± 0.580 | −0.332 ± 0.494 | −0.310 ± 5.09 | 0.137 ± 8.57 | 1.517 ± 11.75 | 0.236 | 0.552 |
5th Ver. coma total | 0.001 ± 0.027 | 0.032 ± 0.064 | 0.149 ± 0.170 | 0.149 ± 0.293 | 0.219 ± 0.525 | <0.001 | <0.001 |
5th Ver. coma front | 0.004 ± 0.068 | 0.152 ± 0.206 | 0.535 ± 0.545 | 0.511 ± 0.958 | 0.718 ± 1.587 | <0.001 | <0.001 |
5th Ver. coma back | −0.01 ± 0.34 | 0.68 ± 0.62 | 1.49 ± 1.43 | 1.45 ± 2.20 | 2.05 ± 2.50 | <0.001 | <0.001 |
5th Hor. coma total | 0.001 ± 0.024 | 0.002 ± 0.045 | 0.002 ± 0.112 | 0.004 ± 0.203 | −0.020 ± 0.320 | 0.723 | 0.815 |
5th Hor. coma front | 0.001 ± 0.053 | 0.009 ± 0.132 | 0.003 ± 0.348 | 0.008 ± 0.682 | −0.083 ± 0.942 | 0.453 | 0.690 |
5th Hor. coma back | −0.001 ± 0.36 | 0.035 ± 0.49 | −0.020 ± 1.18 | −0.041 ± 1.80 | −0.355 ± 2.13 | 0.461 | 0.415 |