Table 4.

QTcF Duration Measurements

QTcF (ms)	Prandial State			Difference
	FO	LFB	HFB	LFB − FO	HFB − FO
Predose baseline
Median	414	407	411	−5	−1
Range	381–497	376–451	380–468	−102 to 33	−80 to 34
Postdose maximum
Median	424	417	421	−3	−5
Range	404–454	394–451	401–449	−15 to 18	−17 to 22
Maximum change
Median	5	10	5	3	−3
Range	1–24	−9 to 36	3–55	−11 to 21	−5 to 46

Abbreviations: QTcF, Fridericia corrected QT interval; FO, fasted overnight; LFB, low-fat breakfast; HFB, high-fat breakfast.