Table 3.

Overall Grade 3 or 4 Toxicity Associated With PEG-IFN-α-2a Therapy

Toxicity	PV (n = 40)				ET (n = 39)				Overall
	Grade 3		Grade 4		Grade 3		Grade 4		Grade 3 or 4
	No.	%	No.	%	No.	%	No.	%	No.	%
Neutropenia	3	8	0	0	12	31	1	3	16	20
Elevated LFTs	2	5	0	0	3	8	0	0	5	6
Fatigue	1	3	0	0	2	5	0	0	3	4
Pain	1	3	0	0	1	3	0	0	2	3
Infection	1	3	0	0	1	3	0	0	2	3
Depression	1	3	0	0	1	3	0	0	2	3
Diarrhea	1	3	0	0	0	0	0	0	1	1
Mucositis	0	0	0	0	1	3	0	0	1	1
Blurred vision	1	3	0	0	0	0	0	0	1	1
Dizziness	1	3	0	0	0	0	0	0	1	1
Anemia	0	0	0	0	1	3	0	0	1	1

Abbreviations: PEG-IFN-α-2a, pegylated interferon alfa-2a; PV, polycythemia vera; ET, essential thrombocythemia; LFTs, liver function tests.