Table 1. Studies of serrated polyps and age.
Author, year | Study description | n with SPs | Age OR/RR* (95% CI) |
---|---|---|---|
All SPs | |||
Erhardt, 2002 [42] | German population Screening/diagnostic colonoscopy | 71 | ≤55 y: 1.00 [ref] >55 y: 1.72 (1.00-2.96) |
Morimoto, 2002 [45] | US population (MN) Screening/diagnostic colonoscopy | 219 | <40 y: 1.0 [ref] 40-49 y: 0.9 (0.4-2.3) 50-59 y: 1.6 (0.7-3.7) 60-69 y: 1.4 (0.6-3.2) ≥70 y: 1.6 (0.5-5.0) |
Lieberman, 2003 [33] | US population (veterans) Screening colonoscopy | 391 | 50-54 y: 1.00 [ref] 55-59 y: 1.10 (0.76-1.60) 60-64 y: 1.05 (0.76-1.46) 65-69 y: 1.01 (0.72-1.41) ≥70 y: 0.70 (0.48-1.02) |
Omata, 2009 [46] | Japanese population, Diagnostic colonoscopy | 132 | |
Burnett-Hartman, 2013 [48] | US population (Group Health, WA) Screening colonoscopy | 594 | |
Proximal/large SPs | |||
Wallace, 2009 [52] | US population (multicenter/PPSG) Proximal SPs | 261 | <61 y: 1.00 [ref] ≥61 y: 0.86 (0.68-1.10) |
Min, 2012 [56] | Korean population Proximal SPs | 60 | ≥70: 1.00 [ref] 60-69: 2.13 (0.62-7.29) 50-59: 1.53 (0.45-5.20) |
Bouwens, 2013 [51] | Dutch population Proximal, large (>6mm) or dysplastic SPs | 141 | |
Burnett-Hartman, 2013 [48] | US population (Group Health, WA) Proximal SPs | 199 | <50 y: 1.00 [ref] 50-59 y: 1.49 (0.70-3.14) 60-69 y: 1.72 (0.77-3.85) ≥70 y: 1.51 (0.60-3.81) |
SSAs | |||
Anderson, 2011 [49] | US population (CT) Pancolonic SSAs | 90 | Per year increase: 1.05 (1.02-1.08) |
Burnett-Hartman, 2013 [48] | US population (Group Health, WA) Pancolonic SSAs | 149 | <50 y: 1.00 [ref] 50-59 y: 1.63 (0.72-3.67) 60-69 y: 2.09 (0.87-5.00) ≥70 y: 2.19 (0.83-5.76) |
Hetzel, 2010 [5] | US population (Boston) Pancolonic SSAs | 46 | Per year increase†: 1.00 (0.96-1.03) |
multivariate adjusted OR reported when provided
Incidence rate ratio
SP: serrated polyp; SSA: sessile serrated adenoma; OR: odds ratio; RR: risk ratio; CI: confidence interval; PPSG: Polyp Prevention study Group
Red text: statistically significant result