Table 2. Concentrations of cannabinoids (THC, THC-A and both THC + THC-A) in mixtures and vapors of BHO diluted in commercial liquid and pure PG.

[% w/w] in liquid refill	Strong decarboxylation (2 hrs, 120 °C) BHO in commercial e-liquid			Soft decarboxylation (4 days, 65 °C) BHO in commercial e-liquid			Strong decarboxylation (2 hrs, 120 °C) BHO in pure PG			Pure BHO not decarboxylated	Smoke of real joint (400 mg tobacco, 400 mg herb at 17% of [THC-A + THC])	Smoke of real cigarette (800 mg tobacco)
	BHO 3%	BHO 5%	BHO 10%	BHO 3%	BHO 5%	BHO 10%	BHO 3%	BHO 5%	BHO 10%
THC in liquid [μg/mg of liquid]	14	14	55	10	12	68	69	68	67	2.5
THC-A in liquid [μg/mg of liquid]	_	_	_	3	6	37.5	_	_	_	765
THC in vapor [μg/mg of liquid]	3.4	2.3	2.5	0.9	2.9	4.3	Not measured	Not measured	9.0		3.75	0 mg
THC-A in vapor [μg/mg of liquid or /cigarette]	_	_	_	_	0.001	0.004	Not measured	Not measured	_		9.4	0 μg
[THC-A + THC] in vapor [μg/mg of liquid]	3.4	2.3	2.5	0.9	2.9	4.4	Not measured	Not measured	9.0		3.75	0 mg
Quantity of cannabinoid liquid refill required to produce similar effects to 1.5 mg of THC i.v. (mg)	1261	1863	1714	4762	1478	997			476
Equivalent in puffs of 70 mL	252	373	343	952	296	199			95
Quantity of cannabinoid liquid refill to induce effects similar to THC contained in the smoke of a real cannabis cigarette (mg)	1103	1630	1500	4167	1293	872			417
Equivalent in puffs of 70 mL	221	326	300	833	259	174			83

(Influence of the decarboxylation conditions, estimation of the quantity of liquid refill consumption to reach a THC concentration of 1.5 mg i.v. [minimal concentration reported for pharmacological effects] and THC and THC-A amounts measured in the whole smoke of a real cannabis cigarette [400 mg tobacco, 400 mg dronabinol cannabis flower tops containing 17% of both THC + THC-A]).

*Assuming a bioavailability of 35% for the cannabinoids contained in the vapor²⁵,²⁹. Bioavailability of vaped and smoked THC is supposed to be the same.