Table 3.
Variant Group (Number) | Genotype Number (%) | Model 1 | Model 2 | Model 3 | ||||
---|---|---|---|---|---|---|---|---|
OR (95% CI) | p-Values | OR (95% CI) | p-Values | OR (95% CI) | p-Values | |||
Dominant model | CC | GG + CG | ||||||
Control (1585) | 483 (30.5) | 1102 (69.5) | 1.00 | 1.00 | 1.00 | |||
Stroke (1139) | 355 (31.2) | 784 (68.8) | 1.03 (0.81–1.31) | 0.801 | 0.98 (0.77–1.25) | 0.870 | 1.00 (0.78–1.27) | 0.961 |
Cerebral thrombosis (718) | 223 (31.1) | 495 (68.9) | 0.97 (0.80–1.18) | 0.778 | 1.03 (0.84–1.25) | 0.792 | 1.02 (0.84–1.24) | 0.834 |
Lacunar infarct (421) | 132 (31.4) | 289 (68.6) | 0.96 (0.76–1.21) | 0.728 | 0.96 (0.76–1.21) | 0.707 | 0.96 (0.76–1.22) | 0.745 |
Recessive model | GC + CC | GG | ||||||
Control (1585) | 1352 (85.3) | 233 (14.7) | 1.00 | 1.00 | 1.00 | |||
Stroke (1139) | 973 (85.4) | 166 (14.6) | 0.99 (0.80–1.23) | 0.927 | 1.02 (0.82–1.27) | 0.868 | 1.00 (0.80–1.24) | 0.985 |
Cerebral thrombosis (718) | 613 (85.4) | 105 (14.6) | 1.01 (0.78–1.29) | 0.962 | 0.97 (0.75–1.25) | 0.813 | 0.99 (0.77–1.28) | 0.950 |
Lacunar infarct (421) | 360 (85.5) | 61 (14.5) | 0.98 (0.73–1.33) | 0.913 | 0.99 (0.73–1.35) | 0.971 | 1.02 (0.75–1.38) | 0.922 |
Abbreviations: OR: Odds ratio; CI: Confidence interval. Model 1: Unadjusted OR; Model 2: Adjusted for age and sex; Model 3: Adjusted for age, sex, hypertension, diabetes mellitus, smoking status, and alcohol intake (adjusted ORs (95% CI) and adjusted p-values were computed using multivariate logistic regression analyses).