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Structural superposition of two zinc-binding fragments containing the HX(2)C sub-pattern, found in PARP (blue) and PHD (magenta) zinc-finger domains. The Trp residues located in the second position before the His ligand (i.e., WXHX(2)C) are shown as sticks. The zinc ions are shown as yellow spheres; the zinc-binding residues are shown as sticks.
