Table 1.
Characteristics of the study population.
| Clinical Variables | ET (n = 50) | ScT (n = 51) | p Value * |
|---|---|---|---|
| Gestational age, wks, median (IQR) | 28 (26–31) | 26 (24–29) | 0.05 |
| Birth weight, g, median (IQR) | 1060 (770–2000) | 750 (580–1100) | 0.003 |
| ≤1000 g, n (%) | 23 (46) | 37 (72.5) | 0.008 |
| 1001–1500 g, n (%) | 11 (22) | 5 (5.8) | 0.11 |
| >1500 g, n (%) | 16 (32) | 9 (17.6) | 0.11 |
| SGA, n (%) | 5 (10) | 13 (25.5) | 0.07 |
| Inborn, n (%) | 44 (88) | 44 (86.3) | 1 |
| Twin, n (%) | 14 (28) | 11 (21.6) | 0.49 |
| Male, n (%) | 31 (62) | 33 (64.7) | 0.83 |
| Apgar 1 min, median (IQR) | 5 (2–7) | 5 (2–6) | 0.43 |
| Apgar 5 min, median (IQR) | 8 (7–8) | 7 (7–8) | 0.66 |
| Resuscitation in delivery room, n (%) 1 | 42 (84) | 45 (88.2) | 0.57 |
| Early-onset sepsis, n (%) | 27 | 14 | 0.008 |
| Late-onset sepsis, n (%) | 23 | 37 | 0.008 |
| Age at sepsis evaluation, d, median (IQR) | 2 (0–11) | 9 (3–22) | 0.003 |
| Weight at sepsis evaluation, g, median (IQR) | 1212.5 (820–1960) | 880 (600–1610) | 0.05 |
| Time between sepsis and septic shock, h, median (IQR) | 4.5 (3–10) | 13 (5–29) | 0.001 |
| Time between septic shock and ET, h, median (IQR) | 7 (4–18) | NA | NA |
* Chi-squared test for categorical variables, Mann–Whitney U test for quantitative variables; ET: Exchange transfusion; ScT: Standard care therapy; IQR: Interquartile range; SGA: Small for gestational age; (1) at least ventilation with mask. Bold number: p Value ≤ 0.05; NA: not applicable.