Table 3.
Clinical characteristics of the study population at the onset of septic shock.
| Clinical Signs/Symptoms | ET (n = 50) | ScT (n = 51) | p Value * |
|---|---|---|---|
| Hyperthermia, n (%) | 6 (12) | 5 (9.8) | 0.76 |
| Hypothermia, n (%) | 6 (12) | 11 (21.6) | 0.28 |
| Respiratory signs, n (%) | – | – | – |
| Any, n (%) | 48 (96) | 50 (98) | 0.6 |
| Apnea, n (%) | 32 (62.7) | 32 (64) | 1 |
| Tachypnea, n (%) | 48 (96) | 49 (96.1) | 1 |
| Feeding intolerance, n (%) | 16 (32) | 29 (56.9) | 0.01 |
| Tachycardia, n (%) | 45 (90) | 35 (68.6) | 0.01 |
| Hypotension, n (%) | 42 (84) | 45 (88.2) | 0.57 |
| Poor capillary refill, n (%) | 45 (90) | 48 (94.1) | 0.48 |
| Neurologic signs, n (%) | – | – | – |
| Any, n (%) | 36 (72) | 40 (78.4) | 0.49 |
| Hypotonia, n (%) | 28 (56) | 36 (70.6) | 0.15 |
| Lethargy, n (%) | 28 (56) | 40 (78.4) | 0.02 |
| Seizures, n (%) | 2 (3.9) | 2 (4) | 1 |
| Diuresis | – | – | – |
| Oliguria/anuria, n (%) | 24 (48) | 15 (29) | 0.14 |
| Oliguria, n (%) | 7 (14) | 4 (8) | 0.35 |
| Anuria, n (%) | 17 (34) | 11 (21) | 0.19 |
| SNAP-II, score, median (IQR) | 32 (19–50) | 41 (25–50) | 0.32 |
| <20 | 13 | 8 | – |
| 20–40 | 15 | 15 | – |
| >40 | 22 | 28 | – |
* Chi-squared test for categorical variables, Mann–Whitney U test for quantitative variables; ET: Exchange transfusion; ScT: Standard care therapy; SNAP-II: Score for Neonatal Acute Physiology-Version II; IQR: Interquartile range. Bold number: p Value ≤ 0.05.