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. 2016 May 17;17(5):744. doi: 10.3390/ijms17050744

Table 3.

Cut-off values of C-peptide indices for need for insulin therapy with 80% specificity. The data are re-calculated from the original data of reference [8] (unpublished data).

Parameter Cut-off Value Specificity (%) Sensitivity (%)
PCPRI 1.53 80 61
FCPRI 0.87 80 45
24 h urinary C-peptide (μg/day) 36.4 80 39

PCPRI; postprandial C-peptide to glucose ratio, FCPRI; fasting C-peptide to glucose ratio. Since PCPRI was measured at 2 h after breakfast during admission, these values may not apply to outpatient settings or other ethnicities. When C-peptide is expressed in nmol/L instead of ng/mL, PCPRI of 1.53 and FCPRI of 0.87 would be 0.51 and 0.29, respectively.