AMPK |
adenosine monophosphate-activated protein kinase |
APE-1/Ref1 |
Apurinic/apyrimidinic endonuclease 1/redox factor 1 |
ApoE |
ApoE, Apolipoprotein E |
ARE |
antioxidant response element |
ATM |
ataxia telangiectasia mutated |
BER |
base excision repair |
CAD |
coronary artery disease |
CDNK2 |
cyclin-dependent kinase inhibitor 2 |
cGMP |
cyclic guanosine monophosphate |
cIMT |
carotid intima media thickness |
CVD |
cardiovascular diseases |
DDB2 |
Damage-Specific DNA Binding Protein 2 |
DNA-PK |
DNA-dependent protein kinase |
DR |
dietary restriction |
eNOS |
endothelial nitric oxide synthase |
EPC |
endothelial progenitor cells |
Ercc1 |
excision repair cross-complementation group 1 |
GH |
growth hormone |
GTF2H |
general transcription factor IIH |
HGPS |
Hutchinson-Gilford progeria syndrome |
HMBG-1 |
high mobility group box 1 |
hMSC |
human mesenchymal stem cells |
HR |
homologous recombination |
IGF1 |
insulin-like growth factor 1 |
IGFBP3 |
insulin-like growth factor-binding protein 3 |
INK-ATTAC mice |
genetically modified mice in which cells expressing the cyclin-dependent kinase inhibitor p16INK4A are being removed by apoptosis due to caspase 8 activation |
LMNA |
lamin A gene |
MMR |
mismatch repair |
MtDNA |
mitochondrial DNA |
mTOR(C1) |
mammalian target of rapamycin (complex 1) |
NADPH |
nicotinamide adenine dinucleotide phosphate |
NER |
nucleotide excision repair |
NHEJ |
non-homologous end joining |
NfkB |
nuclear factor kappa B |
NO |
nitric oxide |
Nrf2 |
transcription factor NF-E2-related factor-2 |
PAI-1 |
plasminogen activator inhibitor-1 |
PARP-1 |
poly [ADP-ribose] polymerase 1 |
PDE |
phosphodiesterase |
POLG |
polymerase gamma |
RecQ |
Escherichia coli recQ-like helicase |
ROS |
reactive oxygen species |
SASP |
senescence-associated secretory phenotype |
(s)GC |
(soluble) guanylyl cyclase |
SIRT-1 |
sirtuin-1 |
SMS |
senescence-messaging secretome |
SNP |
single nucleotide polymorphism |
T2DM |
type 2 diabetes mellitus |
TERC |
RNA template of telomerase |
TERT |
telomerase reverse transcriptase |
TRF2 |
telomeric repeat-binding factor 2 |
TTD |
trichothiodystrophy |
VSMC |
vascular smooth muscle cell |
WRN |
Werner gene |
WS |
Werner Syndrome |
XP |
xeroderma pigmentosum |
XRCC3 |
gene coding for x-ray repair cross-complementing protein 3 |