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19,20-EDP treatment decreased kidney fibrosis in UUO by reducing kidney hydroxyproline content (A); collagen positive area in the kidney (B); and also by reducing kidney mRNA expression of fibronectin (C); representative photomicrographs (200×) showing renal interstitial fibrosis as collagen deposition (arrows) in different experimental groups (D). All data are expressed as Mean ± SEM, * p < 0.05 vs. Sham-Vehicle, # p < 0.05 vs. UUO-Vehicle, n = 6–10.
