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. 2016 May 21;17(5):790. doi: 10.3390/ijms17050790

Table 1.

PD-L1 (programmed death ligand 1) immunohistochemical (IHC) staining criteria for each tumor type.

Tumor Type Percentage pf PD-L1 Positive Tumor Cells PD-L1 Intensity of Reaction PD-L1 Complete Membrane Positivity PD-L1 Incomplete Membrane Positivity PD-L1 Cytoplasmic Positivity
Breast cancer 60% Moderate/Intense + + +/−
Ovarian cancer <10% Moderate + +/−
Thyroid cancer <10% Mild + +
Colon cancer <10% Moderate + +
Lung cancer 10% Moderate + + +
Kidney cancer 20% Moderate + +/−
Melanoma 60% Moderate/Intense + + +/−
Sarcoma 50% Moderate + + +/−
Non-Hodgkin lymphoma 60% Moderate/Intense + +