Table 2.
Operative and postoperative patient characteristics
| Transfem GA (n=51) | Transfem LASedation (n=66) | Transapical (n=59) | |
|---|---|---|---|
| ICU stay (days) | 1 (1-1) | 1 (1-1) | 1 (1-2)* |
| Hospital stay (days) | 9 (7-13) | 7 (5-9)*** | 14 (10-17)* |
| Procedure time (min) | 100 (85-125) | 91 (75-111) | 90 (70-99) |
| Total Intravenous anesthesia (%) | 4 (8) | 1 (6) | 10 (17) |
| Sevoflurane anesthesia (%) | 47 (92) | 3 (4) | 49 (83) |
| Edwards-Sapien (%) | 50 (98) | 55 (83)* | 59 |
| CoreValve (%) | 1 (2) | 5 (8) | 0 |
| Portico (%) | 0 | 6 (9)* | 0 |
| RBC transfusion (%) | 20 (39) | 11 (17)* | 23 (39) |
| Total RBC transfusion; units | 2 (1-3) | 0 (0-1)* | 2 (1-3) |
| Peak troponin-I (ng/mL) | 0.69 (0.49-1.44) | 0.84 (0.45-1.53) | 5.93 (4.36-9.13)* |
| Peak CRP (mg/dL) | 10.2 (5.0-14.0) | 2.4 (1.0-4.7)*** | 22.7 (18.7-26.7)* |
| Postoperative BNP (ng/mL) | 342 (189-659) | 308 (141-872) | 468 (300-843) |
| Discharge Hb (g/dL) | 10.4 (9.6-11.5) | 10.8 (9.6-11.8) | 10.1 (9.5-11.1) |
| Discharge creatinine (mg/dL) | 1.05 (0.91-1.40) | 1.03 (0.78-1.35) | 1.22 (0.92-1.98) |
| Discharge GFR (ml/min) | 55 (41-79) | 60 (42-76) | 49 (29-65) |
All data are expressed in median (percentile 25-75) or numbers (%). *P<0.05: Compared with other two groups, ***P<0.05: In-between transfemoral groups. Transfem GA: Transfemoral general anesthesia, Transfem LASedation: Transfemoral local anesthesia±sedation, ICU: Intensive Care Unit, RBC: Red blood cells, CRP: C- reactive protein, BNP: Brain natriuretic peptide, Hb: Hemoglobin, GFR: Glomerular filtration rate