Table 3.
Uni- and multivariable analysis to predict overall mortality.
| Univariate | Multivariate | |||
|---|---|---|---|---|
|
| ||||
| Variable | OR | p-value | OR | p-value |
|
| ||||
| Steroid treatment | 1.27 | 0.72 | 1.56 | 0.19 |
|
| ||||
| Diagnosis | ||||
| AI-ALF | -- | -- | -- | -- |
| DI-ALF | 1.10 | 0.78 | 1.22 | 0.59 |
| Indeterminate | 1.17 | 0.51 | 1.00 | 1.00 |
|
| ||||
| Age (per 10 years) | 1.37 | <0.001 | 1.39 | <0.001 |
|
| ||||
| Coma grade | ||||
| 1 | -- | -- | -- | -- |
| 2 | 2.02 | 0.03 | 1.74 | 0.12 |
| 3 | 2.65 | 0.006 | 2.37 | 0.02 |
| 4 | 5.29 | <0.001 | 5.18 | <0.001 |
|
| ||||
| Ventilatory Support | 3.11 | <0.001 | -- | -- |
|
| ||||
| MELD | 1.07 | <0.001 | 1.05 | 0.001 |
|
| ||||
| Creatinine (mg/dL) | 1.29 | <0.001 | -- | -- |
|
| ||||
| pH<7.4 | 3.09 | <0.001 | 2.68 | 0.002 |
*
Additional variables tested and not significant with a p<0.2 include: gender, AST, ALT, bilirubin, INR.