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. 2015 Oct 20;4(10):e258. doi: 10.1038/mtna.2015.34

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Copyright © 2015 Official journal of the American Society of Gene & Cell Therapy

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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nkRNA and PnkRNA did not induce expression of IFNβ in murine eyes. To evaluate of activation for innate immune in vivo by nkRNA and PnkRNA, eyes of C57BL/6J mice were injected 1 µg of nkRNA, PnkRNA, or NIRNA. (a) IFNα and (b) IFNβ mRNAs from murine eyes 24 hours after administration mRNA were quantitated by real-time PCR. IFN, interferon.