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. 2016 Feb 16;24(5):956–964. doi: 10.1038/mt.2016.6

Figure 5.

Figure 5

Single-cell detection of time-dependent changes of MCL1 mRNA and Mcl-1 siRNA level at different siRNA dosages. (a) Time-dependent changes of MCL1 mRNA downregulation and self-protection recovery. (b) Comparison of control (without nanochannel electroporation (NEP)), phosphate-buffered saline, scramble siRNA and Mcl-1 siRNA with different dosages on mRNA downregulation. (c) Time-lapse change of Mcl-1 siRNA level at different siRNA dosages. (d) MCL1 mRNA level change with single NEP of low dosage (5 ms) after pretreatment of Act D.