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. Author manuscript; available in PMC: 2016 May 26.
Published in final edited form as: Br J Haematol. 2015 Sep 7;171(4):530–538. doi: 10.1111/bjh.13634

Table 1. Individual IPS factors with FFP and OS by Univariate and Multivariate Analysis.

FFP OS
Univariate Analysis Multivariate Analysis Univariate Analysis Multivariate Analysis
IPS factor HR(95% CI) p-value HR(95% CI) p-value HR(95% CI) p-value HR(95% CI) p-value
Age≥45 years 1.3 (0.9-1.8) 0.15 1.2 (0.9-1.8) 0.27 4.0 (2.7-5.9) <0.0001 3.7 (2.5-5.5) <0.0001
Albumin<4g/dl 1.0 (0.7-1.4) 0.92 0.8 (0.6-1.1) 0.21 1.6 (1.0-2.5) 0.04 1.3 (0.8-2.1) 0.31
WBC≥15,000 mm3 1.3 (0.9-2.0) 0.20 1.3 (0.8-1.9) 0.28 1.1 (0.7-2.0) 0.64 1.2 (0.7-2.1) 0.52
Hgb<10.5g/dl 1.8 (1.3-2.6) 0.0003 1.7 (1.2-2.5) 0.004 2.8 (1.9-4.2) <0.0001 2.1 (1.3-3.3) 0.002
Lymph count <600 mm3or <8% of WBC 1.3 (1.0-1.9) 0.08 1.2 (0.8-1.7) 0.29 1.2 (0.7-1.9) 0.48 1.0 (0.6-1.6) 0.91
Male 1.1 (0.8-1.5) 0.55 1.1 (0.8-1.5) 0.55 1.1 (0.8-1.6) 0.57 1.1 (0.7-1.6) 0.68
Stage IV 1.7 (1.3-2.4) 0.0005 1.5 (1.1-2.1) 0.02 2.3 (1.6-3.4) <0.0001 1.7 (1.1-2.5) 0.02
*

Factors and numbers in bold indicate significant p-values in the analysis.