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. Author manuscript; available in PMC: 2016 May 26.

Published in final edited form as: Br J Haematol. 2015 Sep 7;171(4):530–538. doi: 10.1111/bjh.13634

Table 1. Individual IPS factors with FFP and OS by Univariate and Multivariate Analysis.

	FFP				OS
	Univariate Analysis		Multivariate Analysis		Univariate Analysis		Multivariate Analysis
IPS factor	HR(95% CI)	p-value	HR(95% CI)	p-value	HR(95% CI)	p-value	HR(95% CI)	p-value
Age≥45 years	1.3 (0.9-1.8)	0.15	1.2 (0.9-1.8)	0.27	4.0 (2.7-5.9)	<0.0001	3.7 (2.5-5.5)	<0.0001
Albumin<4g/dl	1.0 (0.7-1.4)	0.92	0.8 (0.6-1.1)	0.21	1.6 (1.0-2.5)	0.04	1.3 (0.8-2.1)	0.31
WBC≥15,000 mm³	1.3 (0.9-2.0)	0.20	1.3 (0.8-1.9)	0.28	1.1 (0.7-2.0)	0.64	1.2 (0.7-2.1)	0.52
Hgb<10.5g/dl	1.8 (1.3-2.6)	0.0003	1.7 (1.2-2.5)	0.004	2.8 (1.9-4.2)	<0.0001	2.1 (1.3-3.3)	0.002
Lymph count <600 mm³or <8% of WBC	1.3 (1.0-1.9)	0.08	1.2 (0.8-1.7)	0.29	1.2 (0.7-1.9)	0.48	1.0 (0.6-1.6)	0.91
Male	1.1 (0.8-1.5)	0.55	1.1 (0.8-1.5)	0.55	1.1 (0.8-1.6)	0.57	1.1 (0.7-1.6)	0.68
Stage IV	1.7 (1.3-2.4)	0.0005	1.5 (1.1-2.1)	0.02	2.3 (1.6-3.4)	<0.0001	1.7 (1.1-2.5)	0.02

^*

Factors and numbers in bold indicate significant p-values in the analysis.