Table IV. Composite and intensity scores for expression of mucin-associated glycans (CA 19-9, TAG72, and Tn/STn on MUC1) in tissues corresponding to normal, inflammation, polyp, adenoma and adenocarcinoma tissues of the colon.

			Diagnosis	Normal	Inflammation	Polyp	Adenoma	CAC	Overall p-value
Mucins associated Glycans	Composite Scores	CA 19-9	Mean ± SE	2.8 ± 0.9	3 ± 1.0	3.3 ± 0.9	3.2 ± 0.6	6.1 ± 1.2	0.3
			Median (Min, Max)	3 (0, 6)	2.5 (0, 9)	2.5 (0, 9)	3 (0, 12)	6 (0, 12)
		TAG72	Mean ± SE	1.7 ± 0.3 10,12	3.5 ± 0.3	4.5 ± 0.5	4.5 ± 0.1 2	5.2 ± 0.2 1	0.093
			Median (Min, Max)	1(0, 4)	2.5 (1, 9)	4 (0, 9)	4 (0, 12)	6 (0, 12)
		Tn/STn on MUC1	Mean ± SE	0.11 ± 0.1 7,9,13	1.3 ± 0.7	2.4 ± 1 1	1.8 ± 0.5 1	3.5 ± 1.0 2	0.077
			Median (Min, Max)	0 (0, 1)	0 (0, 6)	1.5 (0, 9)	0 (0, 9)	2 (0, 12)
	Intensity Scores	CA 19-9	Mean ± SE	1.9 ± 0.5	1.6 ± 0.5	2.1 ± 0.3	1.8 ± 0.2	2.2 ± 0.3	0.71
			Median (Min, Max)	3 (0, 3)	2 (0, 3)	2.5 (0, 3)	2 (0, 3)	3 (0, 3)
		TAG72	Mean ± SE	1.1 ± 0.2 7,10,12	1.7 ± 0.3	2.1 ± 0.3 1	2 ± 0.1 2	2.0 ± 0.2 1	0.043
			Median (Min, Max)	1(0, 2)	1.5 (1, 3)	2 (0, 3)	2 (0, 3)	2 (0, 3)
		Tn/STn on MUC1	Mean ± SE	0.1 ± 0.1 7,9,12	0.5 ± 0.3	1.2 ± 0.4 1	0.9 ± 0.2 1	1.5 ± 0.3 1	0.036
			Median (Min, Max)	0 (0, 1)	0 (0, 2)	1.5 (0, 3)	0 (0, 3)	2 (0, 3)

¹p<0.05 vs. normal;

²p<0.005 vs. normal;

³p<0.0005 vs. normal;

⁴p<0.05 vs. inflammation;

⁵p<0.005 vs. inflammation;

⁶p<0.0005 vs. inflammation;

⁷p<0.05 vs. polyp;

⁸<0.005 vs. polyp;

⁹p<0.05 vs. adenoma;

¹⁰p<0.005 vs. adenoma;

¹¹p<0.0005 vs. adenoma;

¹²p<0.05 vs. adenocarcinoma;

¹³p<0.005 vs. adenocarcinoma;

¹⁴p<0.0005 vs. adenocarcinoma;

colon adenocarcinoma (CAC); standard error (SE); composite score (CS); intensity score (IS)