Table 1. Gender differences in the gut microbiota by BMI at genus level.
Men | Women | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
BMI < 30 | 30 ≤ BMI ≤ 33 | BMI > 33 | P-value | Q-value | BMI < 30 | 30 ≤ BMI ≤ 33 | BMI > 33 | P-value | Q-value | |
Bacteroides | 0.232 ± 0.040 | 0.151 ± 0.025 | 0.019 ± 0.005 | <0.001 | <0.001 | 0.179 ± 0.039 | 0.165 ± 0.045 | 0.134 ± 0.022 | 0.919 | 0.952 |
Dialister | 0.019 ± 0.004 | 0.018 ± 0.009 | 0.004 ± 0.002 | 0.008 | 0.053 | 0.023 ± 0.006 | 0.055 ± 0.015 | 0.007 ± 0.003 | 0.018 | 0.333 |
Prevotella | 0.014 ± 0.008 | 0.014 ± 0.004 | 0.031 ± 0.012 | 0.712 | 0.798 | 0.013 ± 0.005 | 0.010 ± 0.004 | 0.018 ± 0.007 | 0.893 | 0.952 |
Phascolarctobacterium | 0.012 ± 0.004 | 0.017 ± 0.003 | 0.020 ± 0.005 | 0.229 | 0.435 | 0.024 ± 0.005 | 0.011 ± 0.003 | 0.022 ± 0.006 | 0.181 | 0.619 |
Anaerostipes | 0.002 ± 0.001 | 0.001 ± 0.000 | 0.000 ± 0.000 | 0.047 | 0.226 | 0.002 ± 0.001 | 0.001 ± 0.000 | 0.003 ± 0.001 | 0.854 | 0.952 |
Butyricimonas | 0.006 ± 0.001 | 0.004 ± 0.001 | 0.005 ± 0.001 | 0.171 | 0.406 | 0.003 ± 0.001 | 0.002 ± 0.000 | 0.003 ± 0.001 | 0.228 | 0.619 |
Clostridium | 0.016 ± 0.011 | 0.004 ± 0.001 | 0.004 ± 0.001 | 0.960 | 0.960 | 0.002 ± 0.000 | 0.004 ± 0.001 | 0.014 ± 0.008 | 0.732 | 0.952 |
Bilophila | 0.005 ± 0.001 | 0.003 ± 0.001 | 0.003 ± 0.001 | 0.756 | 0.798 | 0.011 ± 0.003 | 0.007 ± 0.002 | 0.005 ± 0.001 | 0.586 | 0.952 |
Roseburia | 0.010 ± 0.002 | 0.015 ± 0.005 | 0.006 ± 0.001 | 0.259 | 0.448 | 0.009 ± 0.002 | 0.007 ± 0.002 | 0.007 ± 0.002 | 0.797 | 0.952 |
Odoribacter | 0.003 ± 0.001 | 0.003 ± 0.000 | 0.003 ± 0.001 | 0.145 | 0.393 | 0.002 ± 0.001 | 0.002 ± 0.000 | 0.001 ± 0.000 | 0.115 | 0.619 |
Streptococcus | 0.021 ± 0.005 | 0.018 ± 0.012 | 0.016 ± 0.006 | 0.117 | 0.369 | 0.009 ± 0.003 | 0.012 ± 0.004 | 0.012 ± 0.002 | 0.624 | 0.952 |
Dorea | 0.002 ± 0.000 | 0.005 ± 0.002 | 0.002 ± 0.001 | 0.202 | 0.426 | 0.009 ± 0.004 | 0.002 ± 0.001 | 0.002 ± 0.001 | 0.228 | 0.619 |
Sutterella | 0.016 ± 0.003 | 0.016 ± 0.003 | 0.020 ± 0.003 | 0.601 | 0.798 | 0.015 ± 0.005 | 0.026 ± 0.009 | 0.017 ± 0.004 | 0.744 | 0.952 |
Ruminococcus | 0.012 ± 0.003 | 0.021 ± 0.006 | 0.019 ± 0.005 | 0.589 | 0.798 | 0.011 ± 0.002 | 0.014 ± 0.007 | 0.024 ± 0.006 | 0.186 | 0.619 |
Parabacteroides | 0.012 ± 0.002 | 0.017 ± 0.005 | 0.018 ± 0.006 | 0.679 | 0.798 | 0.014 ± 0.003 | 0.023 ± 0.006 | 0.022 ± 0.006 | 0.641 | 0.952 |
Oscillospira | 0.012 ± 0.003 | 0.010 ± 0.001 | 0.010 ± 0.002 | 0.732 | 0.798 | 0.018 ± 0.003 | 0.010 ± 0.001 | 0.027 ± 0.009 | 0.042 | 0.403 |
Lachnospira | 0.025 ± 0.007 | 0.011 ± 0.004 | 0.017 ± 0.006 | 0.076 | 0.287 | 0.016 ± 0.006 | 0.017 ± 0.006 | 0.023 ± 0.006 | 0.541 | 0.952 |
Coprococcus | 0.009 ± 0.003 | 0.009 ± 0.001 | 0.011 ± 0.003 | 0.494 | 0.781 | 0.008 ± 0.002 | 0.005 ± 0.001 | 0.006 ± 0.001 | 0.952 | 0.952 |
Blautia | 0.003 ± 0.001 | 0.003 ± 0.001 | 0.001 ± 0.000 | 0.007 | 0.053 | 0.004 ± 0.002 | 0.002 ± 0.000 | 0.002 ± 0.000 | 0.726 | 0.952 |
BMI: body mass index. Rows: comparison of the abundance of the different bacterial genera between different BMI ranges in men and women together and in men and women separately by the Kruskal-Wallis test. Q-value: False Discovery Rate (FDR) using Benjamini and Hochberg method.