Fig 2. Long-term graft function after mouse islet transplantation.
(A) The proportion of animals that achieved normoglycemia. Normoglycemia was restored in 6 animals from the EMP group compared to 1 from the IP group. This difference was statistically significant (P = 0.0183, Log-rank, Mantel-Cox test). All animals from the kidney capsule group were restored to normoglycemia compared to EMP and IP groups (P< 0.01 & 0.0001 respectively, Log-rank, Mantel-Cox test). Transplanted islets were from five different mouse isolations (n = 30 pancreata per isolation). (B) Average non-fasting blood glucose levels for kidney capsule group (KC500), intraperitoneal free islets group (IP500) and seeded microscaffold group (EMP500). Data are presented as mean ± SEM (one-sided error bars for clarity).
