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. 2016 May 26;11(5):e0156260. doi: 10.1371/journal.pone.0156260

Fig 1. RanGAP1 protein level was increased in CML cells compared with that in normal cells.

Fig 1

(A) The RanGAP1 protein levels were measured using an immunoblot assay in normal granulocytes and monocytes from healthy volunteers, and CML cell lines. GAPDH was used as an internal control. Phosphorylated CRKL (Tyr-207) is a marker of active BCR-ABL in CML cells. (B) The quantitative data indicate the RanGAP1 protein levels in normal monocytes and CML cell lines from (A). Results are presented as means + SD of three independent experiments. *p < 0.05, compared with the control.