Table 2. Summary of the studies that are included in this analysis.
| First Author (Year) | Journal | Subjects (N) | Serum IGF-1 (ng/ml) | CSF IGF-1 (ng/ml) |
|---|---|---|---|---|
| Alvarez, A. (2007)[50] | Neurobiol Aging | 171 | IGF-1 ↓ in AD | - |
| Duron, E. (2012)[48] | J Clin Endocrinol Metab | 437 | IGF-1 ↓ in AD men | - |
| Ghigo, E. (1993)[44] | Dement Geriatr Cogn | 29 | IGF-1 ↑ in AD | - |
| Hertze, J. (2014)[49] | Bmc Neurology | 164 | No Change | No Change |
| Mustafa, A. (1999)[51] | Dement Geriatr Cogn | 15 | IGF-1 ↓ in AD | - |
| Salehi, Z. (2008)[45] | Biofactors | 82 | IGF-1 ↑ in AD | IGF-1 ↑ in AD |
| Trueba-Saiz, A. (2013)[42] | Translational Psychiatry | 45 | IGF-1 ↑ in AD | IGF-1 ↓ in AD |
| Vardy, E. (2007)[46] | J Alzheimers Dis | 213 | IGF-1 ↑ in AD | - |
| Vargas, T. (2011)[47] | Neurobiol Aging | 232 | IGF-1 ↑ in AD | - |
| Watanabe, T. (2005)[52] | J Am Geriatr Soc | 333 | IGF-1 ↓ in AD | - |