Fig 1.

a) Schematic representation of SEAM architecture composed of PMMA housings with embedded magnets, PDMS channels, and a removable cell culture insert. b) Images of the removable culture inserts including porous track etched (top) and soft self-assembled (bottom) culture regions. Scale bar = 1 mm. c) Assembled SEAM culture module with top and bottom microfluidic channels filled with red and blue dyes to demonstrate distinct fluidic compartments within a magnetically sealed architecture.